Description

4-Aminocarbonylphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in the stability provided by the pinacol ester group, which protects the reactive boronic acid moiety during synthesis, making it an essential reagent for cross-coupling reactions. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboron reagent for constructing biaryl and heterobiaryl scaffolds, central to many drug molecules.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), especially those containing an amide-linked aromatic moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organometallic catalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is required.
• Chemical Biology & Proteomics: Can be utilized in the development of activity-based probes and other tools for studying biological systems.
• Agrochemical Synthesis: Acts as an intermediate in creating advanced herbicides and fungicides with specific targeting properties.

Basic Information

Product Name	4-Aminocarbonylphenylboronic Acid, Pinacol Ester
CAS No.	179117-44-3
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	4-Carbamoylphenylboronic Acid Pinacol Ester; 4-Aminocarbonylbenzeneboronic Acid Pinacol Ester; (4-Carbamoylphenyl)boronic Acid Pinacol Ester; 4-Pinacolatoborylbenzamide; B-(4-Aminocarbonylphenyl)boronic Acid Pinacol Ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 179117-44-3; Benzamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 4-Aminocarbonylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.