Description

Cyclohexanecarboxylic Acid, 3-Amino-1,4-Dihydroxy-5-Oxo-, [1R-(1Alpha,3Beta,4Alpha)]- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the synthesis of novel therapeutic agents, agrochemicals, and other fine chemicals where precise stereochemistry is critical for function.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in classes requiring complex polyfunctional cyclohexane scaffolds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators where its specific stereochemistry can influence biological activity and selectivity.
• Fine Chemical Production: Serves as a specialized building block for synthesizing complex molecules used in dyes, pigments, and advanced material science applications.
• Biochemical Research: Employed in academic and industrial R&D as a probe or precursor in studying enzyme mechanisms and designing enzyme inhibitors.
• Asymmetric Catalysis Ligand Precursor: Its functional groups make it a potential starting material for developing novel chiral ligands and catalysts used in stereoselective transformations.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 3-Amino-1,4-Dihydroxy-5-Oxo-, [1R-(1Alpha,3Beta,4Alpha)]-
CAS No.	178948-65-7
Molecular Formula	C7H11NO5
Molecular Weight	189.17 g/mol
Synonyms	(1R,3S,4R)-3-Amino-1,4-dihydroxy-5-oxocyclohexane-1-carboxylic acid; (1R,3S,4R)-3-Amino-1,4-dihydroxy-5-oxocyclohexanecarboxylic acid; 3-Amino-1,4-dihydroxy-5-oxocyclohexanecarboxylic acid (1R,3S,4R)-; 5-Oxo-3-amino-1,4-dihydroxycyclohexanecarboxylic acid; Chiral Cyclohexane Amino Dihydroxy Oxo Acid; CAS 178948-65-7
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 3-Amino-1,4-Dihydroxy-5-Oxo-, [1R-(1Alpha,3Beta,4Alpha)]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.