Description

4-Chloro-2-Methyl-5-Nitrobenzonitrile is a versatile nitrile-substituted aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, methyl, and nitro functional groups, makes it an invaluable intermediate for constructing complex molecules. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its nitro and nitrile functionalities.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Dye and Pigment Intermediate: Employed in the synthesis of complex azo dyes and organic pigments due to its substituted benzene ring.
• Organic Synthesis Building Block: A versatile reagent for cross-coupling reactions, nucleophilic aromatic substitution, and cyano group transformations in custom synthesis.

Basic Information

Product Name	4-Chloro-2-Methyl-5-Nitrobenzonitrile
CAS No.	178448-14-1
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	5-Nitro-2-methyl-4-chlorobenzonitrile; 2-Methyl-4-chloro-5-nitrobenzonitrile; 4-Chloro-2-methyl-5-nitrobenzenecarbonitrile; Benzonitrile, 4-chloro-2-methyl-5-nitro-; 178448-14-1; 4-Chloro-2-methyl-5-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Methyl-5-Nitrobenzonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. Our standard grade meets the rigorous demands of industrial and research applications, with specifications consistently verified by HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.