Description

(+)-1,2-Bis((2R,5R)-Dimethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Triflate is a high-purity, chiral organorhodium complex widely recognized as a highly effective asymmetric hydrogenation catalyst. Its core value lies in enabling the production of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs) with exceptional selectivity and yield. This catalyst is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic processes.

Application

• Asymmetric Hydrogenation Catalyst: Primary application for the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Critical for manufacturing chiral building blocks and active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Synthesis: Enables the production of high-value chiral compounds for flavors, fragrances, and advanced materials.
• Academic and Process R&D: A valuable tool for methodology development and scaling up novel asymmetric transformations in academic and industrial research laboratories.
• Catalyst Ligand Precursor: The dimethylphospholano ligand framework can be modified or studied for the development of next-generation chiral catalysts.

Basic Information

Product Name	(+)-1,2-Bis((2R,5R)-Dimethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Triflate
CAS No.	177750-25-3
Molecular Formula	C₂₀H₃₇F₃O₃P₂RhS
Molecular Weight	603.42 g/mol
Synonyms	(R,R)-Me-DuPhos Rhodium(I) Triflate Cyclooctadiene Complex; [(R,R)-Me-DuPhos)Rh(COD)]OTf; (R,R)-1,2-Bis(2,5-dimethylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; (R,R)-Me-DuPhos-Rh-COD-OTf; Rh-((R,R)-Me-DuPhos)(COD)OTf; (R,R)-Me-DuPhos Rhodium Catalyst; DuPhos Rhodium Triflate Catalyst; Asymmetric Hydrogenation Catalyst Rh-Me-DuPhos
EINECS	Contact for details

Quality Control

Our (+)-1,2-Bis((2R,5R)-Dimethylphospholano)Ethane(Cyclooctadiene)Rhodium(I) Triflate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure consistency and catalytic performance. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade the catalyst.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Rhodium Content	Contact for details
Solubility	Soluble in dichloromethane, acetone, THF; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.