Description

2,5-Dichlorothiophene-3-Boronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in cross-coupling reactions, enabling the precise construction of complex heterocyclic molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those containing functionalized thiophene cores.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for palladium-catalyzed coupling with aryl/heteroaryl halides to form biaryl structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the creation of organic semiconductors, conductive polymers, and liquid crystals for electronic applications.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs serving the global chemical industry.

Basic Information

Product Name	2,5-Dichlorothiophene-3-Boronic Acid
CAS No.	177735-28-3
Molecular Formula	C4H3BCl2O2S
Molecular Weight	210.84 g/mol
Synonyms	(2,5-Dichloro-3-thienyl)boronic acid; 2,5-Dichloro-3-thiopheneboronic acid; 2,5-Dichlorothiophene-3-boronic acid; 3-Borono-2,5-dichlorothiophene; (2,5-Dichlorothiophen-3-yl)boronic acid; B-(2,5-Dichloro-3-thienyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dichlorothiophene-3-Boronic Acid is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support applications requiring high standards, including cGMP manufacturing where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.