Description

Ethanone, 1-(5-Amino-2-Thienyl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a reactive amino-thiophene backbone. This compound matters as a high-value pharmaceutical intermediate and building block for synthesizing complex molecules, particularly in medicinal chemistry. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the bioactivity of the trifluoromethyl and thiophene groups.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials in electronic displays.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic processes.
• Fluorinated Compound Research: Acts as a standard or starting material in academic and industrial R&D focused on introducing fluorine into complex molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	Ethanone, 1-(5-Amino-2-Thienyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	177411-86-8
Molecular Formula	C7H4F3NOS
Molecular Weight	207.17 g/mol
Synonyms	1-(5-Amino-2-thienyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(5-amino-2-thienyl)ethanone; 5-Amino-2-thenoyltrifluoride; 5-Amino-2-thienyl trifluoromethyl ketone; 2-Thienyl, 5-amino-, trifluoromethyl ketone; 1-(5-Amino-2-thienyl)-2,2,2-trifluoroethan-1-one; Trifluoroacetyl-5-aminothiophene
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(5-Amino-2-Thienyl)-2,2,2-Trifluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.