Description

Ethanone, 1-(2,4-Difluoro-5-Methylphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is crucial for modulating biological activity and metabolic stability. Industries that require high-purity, custom synthetic intermediates for research and development, including pharmaceutical R&D, agrochemical manufacturing, and advanced material science, are the primary users of this product.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics where fluorination enhances drug properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine substituents to improve efficacy, selectivity, and environmental stability of the final product.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials that require specific fluorinated aromatic structures.
• Chemical Research & Development: Employed as a versatile building block in academic and industrial R&D for exploring new reaction methodologies, creating compound libraries for screening, and developing novel fluorinated chemical entities.
• Dye and Pigment Intermediate: Acts as a key component in the synthesis of advanced fluorinated dyes and pigments, which often exhibit superior lightfastness and unique chromatic properties.

Basic Information

Product Name	Ethanone, 1-(2,4-Difluoro-5-Methylphenyl)- (9Ci)
CAS No.	177211-27-7
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(2,4-Difluoro-5-methylphenyl)ethanone; 2',4'-Difluoro-5'-methylacetophenone; 5-Methyl-2,4-difluoroacetophenone; 2,4-Difluoro-5-methylacetophenone; 1-Acetyl-2,4-difluoro-5-methylbenzene; 2,4-Difluoro-5-methylphenyl methyl ketone; (2,4-Difluoro-5-methylphenyl)ethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2,4-Difluoro-5-Methylphenyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.