Description

1-Dodecylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its primary value lies in providing a stable, shelf-stable form of the reactive dodecylboronic acid, ensuring consistent performance and simplified handling for industrial-scale processes. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex organic molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for introducing long alkyl chains (dodecyl groups) into biaryl and heteroaryl structures in pharmaceutical and agrochemical intermediates.
• Organic Light-Emitting Diodes (OLEDs) & Electronic Materials: Used in the synthesis of organic semiconductors and charge-transport materials where specific alkyl chain length is crucial for solubility and film-forming properties.
• Liquid Crystal & Polymer Synthesis: Serves as a monomer or modifier for creating side-chain polymers and liquid crystalline compounds with tailored mesomorphic properties.
• Surface Modification & Ligand Synthesis: Employed to create hydrophobic coatings or to synthesize ligands for catalysis and nanotechnology applications.
• Medicinal Chemistry & Drug Discovery: Utilized in library synthesis for structure-activity relationship (SAR) studies, particularly for compounds requiring lipophilic side chains.
• Agrochemical Active Ingredients: A precursor in the synthesis of herbicides and fungicides that incorporate long-chain alkyl motifs for enhanced bioavailability and efficacy.

Basic Information

Product Name	1-Dodecylboronic Acid Pinacol Ester
CAS No.	177035-82-4
Molecular Formula	C18H37BO2
Molecular Weight	296.30 g/mol
Synonyms	Dodecylboronic Acid Pinacol Ester; Laurylboronic Acid Pinacol Ester; (Dodecylboronic Acid) Pinacol Ester; Pinacol Dodecylboronate; 1-Dodecyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-Dodecyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; LaurylBPin; n-DodecylBPin
EINECS	Contact for details

Quality Control

Our 1-Dodecylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.