Description

(1S)-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3,3'-Dicarboxaldehyde is a high-purity, chiral binaphthyl derivative that serves as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in its role as a key building block for constructing complex, enantiomerically pure ligands and catalysts, which are essential for asymmetric transformations. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Asymmetric Catalyst Synthesis: A vital precursor for the preparation of chiral phosphine, phosphite, and N-heterocyclic carbene (NHC) ligands used in enantioselective hydrogenation, cross-coupling, and cycloaddition reactions.
• Pharmaceutical Intermediate: Employed in the research and development of enantiomerically pure drug candidates, particularly in therapeutic areas requiring high stereochemical fidelity.
• Material Science Research: Used in the synthesis of chiral polymers, macrocycles, and supramolecular structures with potential applications in sensors and advanced materials.
• Ligand Library Development: Serves as a core scaffold for creating diverse libraries of chiral ligands for high-throughput screening in catalysis research.

Basic Information

Product Name	(1S)-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3,3'-Dicarboxaldehyde
CAS No.	176437-91-5
Molecular Formula	C26H22O6
Molecular Weight	430.45 g/mol
Synonyms	(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene-3,3'-dicarboxaldehyde; (S)-3,3'-Dicarboxy-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; (S)-BINOL-DiCHO-MOM; (1S)-BINOL Derivative; (S)-BINOL Dialdehyde MOM Ether; (S)-2,2'-Di(methoxymethoxy)-1,1'-binaphthyl-3,3'-dicarbaldehyde; (S)-MOM-Protected BINOL Dialdehyde
EINECS	Contact for details

Quality Control

Our (1S)-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3,3'-Dicarboxaldehyde is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity, critical for sensitive asymmetric synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and identity confirmation. We adhere to relevant industry standards for fine chemical intermediates, and specifications can be aligned with specific research or cGMP requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.