Description

2-Chloro-5-Hydroxy-3-Pyridinecarboxaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both aldehyde and hydroxyl groups on a chlorinated pyridine ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors, antiviral agents, and other biologically active heterocyclic compounds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional organic molecules for electronic materials, sensors, and advanced polymers.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry programs and library synthesis in high-throughput screening.

Basic Information

Product Name	2-Chloro-5-Hydroxy-3-Pyridinecarboxaldehyde
CAS No.	176433-62-8
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	5-Hydroxy-2-chloropyridine-3-carbaldehyde; 2-Chloro-5-hydroxynicotinaldehyde; 3-Formyl-2-chloro-5-hydroxypyridine; 2-Chloro-5-hydroxypyridine-3-carboxaldehyde; 2-Chloro-5-pyridinol-3-carboxaldehyde; 176433-62-8; 2-Chloro-5-hydroxy-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Hydroxy-3-Pyridinecarboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.