Description

Ethyl 2-Oxobicyclo[3.1.0]Hexane-6-Carboxylate (Ws200253) is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile chiral building block for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile building block for constructing novel molecular scaffolds in drug discovery programs.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of target molecules.
• Asymmetric Synthesis: Exploits its inherent chirality for the construction of enantiomerically pure compounds in fine chemical manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis and development projects.
• Academic Research: Employed in university and institutional labs for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name	Ethyl 2-Oxobicyclo[3.1.0]Hexane-6-Carboxylate (Ws200253)
CAS No.	176199-53-4
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	Ethyl 6-oxabicyclo[3.1.0]hexane-2-carboxylate; Ethyl bicyclo[3.1.0]hexane-6-carboxylate-2-one; 6-Carbethoxy-2-oxobicyclo[3.1.0]hexane; WS-200253; Ws200253; 176199-53-4; Ethyl 2-oxobicyclo[3.1.0]hexane-6-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Oxobicyclo[3.1.0]Hexane-6-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.