Description

Cyclobutanecarboxaldehyde, 2-Phenyl-, cis- (9Ci) is a specialized chiral aldehyde building block of significant interest in advanced organic synthesis. Its value lies in the unique steric and electronic properties conferred by the cis-configured phenyl-substituted cyclobutane ring, which is crucial for constructing complex molecular architectures with high stereochemical fidelity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, fragrances, and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where its structure can impart specific biological activity.
• Asymmetric Catalysis & Ligand Development: Serves as a starting material for synthesizing novel chiral ligands and catalysts used in enantioselective transformations.
• Fragrance & Flavor Chemistry: Employed in the creation of complex, stereodefined aroma molecules for high-end perfumery and flavor applications.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with unique thermal and mechanical properties.
• Academic & Institutional Research: A valuable tool for methodological studies in organic chemistry, particularly in cyclobutane chemistry and stereoselective synthesis.

Basic Information

Product Name	Cyclobutanecarboxaldehyde, 2-Phenyl-, cis- (9Ci)
CAS No.	176172-02-4
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	cis-2-Phenylcyclobutanecarboxaldehyde; (1S,2R)-2-Phenylcyclobutanecarbaldehyde; (1R,2S)-2-Phenylcyclobutanecarbaldehyde; 2-Phenylcyclobutanecarboxaldehyde, cis-; 2-Phenylcyclobutanecarbaldehyde; Cyclobutanecarboxaldehyde, 2-phenyl-, cis-; (cis)-2-Phenylcyclobutanecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxaldehyde, 2-Phenyl-, cis- (9Ci) is produced and controlled under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure identity, purity, and enantiomeric excess meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed and away from heat and ignition sources. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.