Description

4-(1,1,2,3,3,3-Hexafluoropropoxy)-Biphenyl is a high-value fluorinated aromatic ether compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring a hexafluoropropoxy group, provides exceptional thermal stability, chemical resistance, and specific electronic properties sought after in high-performance applications. This compound is primarily required by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorinated side chain improves efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a core component or side-chain modifier in the development of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Employed in the synthesis of semiconductors, charge-transport materials, and emissive layers for OLEDs and organic photovoltaics due to its electron-withdrawing characteristics.
• Polymer Modification: Acts as a monomer or grafting agent to introduce fluorine into polymer backbones, enhancing material properties like solvent resistance, thermal stability, and low surface energy for coatings.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new fluorination chemistry, cross-coupling reactions, and material science innovations.

Basic Information

Product Name	4-(1,1,2,3,3,3-Hexafluoropropoxy)-Biphenyl
CAS No.	175838-51-4
Molecular Formula	C15H10F6O
Molecular Weight	320.23 g/mol
Synonyms	4-(Hexafluoroisopropoxy)biphenyl; 4-(1,1,2,3,3,3-Hexafluoropropoxy)-1,1'-biphenyl; Biphenyl, 4-(1,1,2,3,3,3-hexafluoropropoxy)-; 4-(Perfluoroisopropoxy)biphenyl; 4-(HFP-O)-Biphenyl; [1,1'-Biphenyl]-4-ol, 4-(1,1,2,3,3,3-hexafluoropropoxy)-; 4-(α,β,β-Trifluorovinyloxy)biphenyl derivative
EINECS	Contact for details

Quality Control

Our 4-(1,1,2,3,3,3-Hexafluoropropoxy)-Biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.