Description

Cyclopropanecarboxaldehyde, 1-Methyl-2-Phenyl-, cis- (9Ci) is a specialized chiral aldehyde building block featuring a cyclopropane ring, a phenyl group, and a methyl substituent in a defined cis configuration. This compound is valued for its unique three-dimensional structure, which imparts specific steric and electronic properties critical for synthesizing complex molecules with targeted biological activity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide intermediates, where the cyclopropane moiety can enhance metabolic stability and binding affinity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new stereoselective synthetic methodologies.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of complex aroma chemicals, leveraging its unique structural motif to create novel scent profiles.
• Material Science Precursor: Can be employed in the synthesis of specialized monomers or ligands for advanced polymeric materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 1-Methyl-2-Phenyl-, cis- (9Ci)
CAS No.	175788-15-5
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	cis-1-Methyl-2-phenylcyclopropanecarboxaldehyde; (1S,2R)-1-Methyl-2-phenylcyclopropanecarbaldehyde; (1R,2S)-1-Methyl-2-phenylcyclopropanecarbaldehyde; 1-Methyl-2-phenylcyclopropanecarboxaldehyde, cis-; 1-Methyl-2-phenylcyclopropanecarbaldehyde; cis-1-Methyl-2-phenylcyclopropanecarbaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 1-Methyl-2-Phenyl-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) providing identity, assay, and impurity profiles is supplied with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.