Description

2,4-Difluorobenzene-1-Carbothioamide is a specialized fluorinated aromatic carbothioamide building block. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its difluorobenzene core and thioamide functionality are leveraged for bioactivity and metabolic stability. It is primarily needed by research chemists and process development scientists working on novel active ingredients, including kinase inhibitors and herbicides.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new herbicides and pesticides, utilizing the fluorine atoms to enhance biological activity and environmental persistence.
• Chemical Synthesis: Used in organic synthesis as a versatile reagent for constructing complex heterocycles and functionalized aromatic systems.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or chemical resistance properties.
• Ligand and Catalyst Development: Employed in the design of novel ligands for metal catalysis due to the coordinating potential of the thioamide group.

Basic Information

Product Name	2,4-Difluorobenzene-1-Carbothioamide
CAS No.	175276-92-3
Molecular Formula	C7H5F2NS
Molecular Weight	173.18 g/mol
Synonyms	2,4-Difluorobenzothioamide; 2,4-Difluorobenzenecarbothioamide; 1-Carbamothioyl-2,4-difluorobenzene; 2,4-Difluorophenylcarbothioamide; 2,4-Difluorothiobenzamide; NSC 405124; AI3-52031; BRN 7422780
EINECS	Contact for details

Quality Control

Our 2,4-Difluorobenzene-1-Carbothioamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.