Description

4-Fluorobenzylsulfonylacetonitrile is a high-value fluorinated organic intermediate characterized by its reactive sulfonyl and nitrile functional groups. This compound is essential for the synthesis of complex molecules, offering chemists a versatile building block for introducing specific fluorinated motifs. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorinated benzylsulfonyl moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and other functional materials with tailored properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and cyclization processes to construct complex heterocyclic compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	4-Fluorobenzylsulfonylacetonitrile
CAS No.	175276-84-3
Molecular Formula	C9H8FNO2S
Molecular Weight	213.23 g/mol
Synonyms	Acetonitrile, [(4-fluorophenyl)methyl]sulfonyl-; [(4-Fluorophenyl)methyl]sulfonylacetonitrile; 4-Fluorobenzylsulfonyl Acetonitrile; p-Fluorobenzylsulfonylacetonitrile; (4-Fluorobenzylsulfonyl)acetonitrile; 2-[(4-Fluorobenzyl)sulfonyl]acetonitrile; 4-Fluoro-α-(sulfonylacetonitrile)toluene; 175276-84-3
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzylsulfonylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.