Description

2',6'-Dichloro-4'-(Trifluoromethyl)Acetophenone is a high-purity, specialized organic intermediate featuring a unique trifluoromethyl-substituted aromatic ketone structure. This compound matters for its role as a critical building block in the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its distinct halogen and fluorine pattern enables precise structural modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a vital building block for developing new-generation herbicides and fungicides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty polymers and advanced organic electronic materials due to its electron-withdrawing substituents.
• Ligand and Catalyst Development: Employed in organic chemistry research for creating novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) in fluorinated aromatic systems.

Basic Information

Product Name	2',6'-Dichloro-4'-(Trifluoromethyl)Acetophenone
CAS No.	175205-88-6
Molecular Formula	C9H5Cl2F3O
Molecular Weight	257.04 g/mol
Synonyms	1-(2,6-Dichloro-4-(trifluoromethyl)phenyl)ethan-1-one; 2,6-Dichloro-α,α,α-trifluoro-p-acetophenone; 2',6'-Dichloro-4'-trifluoromethylacetophenone; 2,6-Dichloro-4-(trifluoromethyl)acetophenone; α,α,α-Trifluoro-2,6-dichloro-4-acetylbenzene; 1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]ethanone; Acetophenone, 2',6'-dichloro-4'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2',6'-Dichloro-4'-(Trifluoromethyl)Acetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.