Description

2,3,4-Trifluorophenylthiourea is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its value lies in its unique molecular structure, which combines a thiourea moiety with a multi-fluorinated phenyl ring, making it a versatile precursor for pharmaceuticals and agrochemicals. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for creating thiourea-based organocatalysts and metal-complexing ligands used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique thermal and chemical resistance properties.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for developing enzyme inhibitors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.

Basic Information

Product Name	2,3,4-Trifluorophenylthiourea
CAS No.	175205-26-2
Molecular Formula	C7H5F3N2S
Molecular Weight	206.19 g/mol
Synonyms	1-(2,3,4-Trifluorophenyl)thiourea; N-(2,3,4-Trifluorophenyl)thiourea; 2,3,4-Trifluorophenyl-thiourea; Thiourea, N-(2,3,4-trifluorophenyl)-; 2,3,4-Trifluoro-phenylthiourea; (2,3,4-Trifluorophenyl)thiourea; 175205-26-2
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorophenylthiourea is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.