Description

2-tert-Butyl-7-Chloro-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine is a high-value, heterocyclic organic compound featuring a pyrazolopyrimidine core substituted with chloro and trifluoromethyl groups. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Acts as a building block for creating novel organic electronic materials or specialty polymers.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its unique substitution pattern.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Utilized in chemical libraries for high-throughput screening and discovery of new biologically active molecules.

Basic Information

Item	Details
Product Name	2-tert-Butyl-7-Chloro-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine
CAS No.	175203-38-0
Molecular Formula	C11H10ClF3N3
Molecular Weight	276.66 g/mol
Synonyms	2-tert-Butyl-7-chloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 7-Chloro-2-tert-butyl-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 175203-38-0; Pyrazolo[1,5-a]pyrimidine, 2-(1,1-dimethylethyl)-7-chloro-5-(trifluoromethyl)-; 2-(tert-Butyl)-7-chloro-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 2-tert-Butyl-7-Chloro-5-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.