Description

5,7-Difluoro-2,3-Dihydrobenzo[B]Furan is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a critical precursor for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require specialized intermediates for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the difluoro motif can enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers.
• Ligand and Catalyst Development: Serves as a backbone for designing novel ligands in asymmetric catalysis and transition metal complexes.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-fidelity fluorinated intermediates.

Basic Information

Product Name	5,7-Difluoro-2,3-Dihydrobenzo[B]Furan
CAS No.	175203-20-0
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	5,7-Difluoro-2,3-dihydro-1-benzofuran; 2,3-Dihydro-5,7-difluorobenzo[b]furan; Benzo[b]furan, 2,3-dihydro-5,7-difluoro-; 5,7-Difluorodihydrobenzofuran; 175203-20-0; 5,7-Difluoro-2,3-dihydrobenzofuran
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-2,3-Dihydrobenzo[B]Furan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for GLP (Good Laboratory Practice) or cGMP (current Good Manufacturing Practice) applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.