Description

2-[1-Methyl-5-(Trifluoromethyl)Pyrazol-3-Yl]-Thiophene-5-Carboxaldehyde is a high-value heterocyclic building block featuring a fused pyrazole-thiophene core with a reactive aldehyde functional group. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical active ingredients, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and specialty polymers.
• Chemical Biology: Employed as a probe or linker molecule due to its reactive aldehyde group for bioconjugation strategies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke chemical synthesis and scale-up projects.

Basic Information

Item	Details
Product Name	2-[1-Methyl-5-(Trifluoromethyl)Pyrazol-3-Yl]-Thiophene-5-Carboxaldehyde
CAS No.	175202-93-4
Molecular Formula	C10H7F3N2OS
Molecular Weight	260.24 g/mol
Synonyms	1-Methyl-3-(5-formylthiophen-2-yl)-5-(trifluoromethyl)-1H-pyrazole; 5-Formyl-2-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophene; Thiophene-5-carboxaldehyde, 2-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-; 2-(1-Methyl-5-trifluoromethyl-1H-pyrazol-3-yl)thiophene-5-carbaldehyde; 175202-93-4; 2-[1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophene-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-[1-Methyl-5-(Trifluoromethyl)Pyrazol-3-Yl]-Thiophene-5-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.