Description

4-(4-Fluorobenzyloxy)-3-Nitroacetophenone is a specialized aromatic ketone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a fluorobenzyl ether and a nitroacetophenone moiety, makes it a valuable building block for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its nitro and fluoro-substituted aromatic system.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of advanced polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, reduction of nitro groups, and ether cleavage studies to create diverse chemical libraries for screening.
• Academic & Industrial R&D: Essential reagent for method development and scale-up studies in process chemistry within university laboratories and corporate R&D centers.

Basic Information

Item	Detail
Product Name	4-(4-Fluorobenzyloxy)-3-Nitroacetophenone
CAS No.	175136-24-0
Molecular Formula	C15H12FNO4
Molecular Weight	289.26 g/mol
Synonyms	1-[4-[(4-Fluorophenyl)methoxy]-3-nitrophenyl]ethanone; 3'-Nitro-4'-(4-fluorobenzyloxy)acetophenone; 4-Fluorobenzyl 3-nitro-4-acetylphenyl ether; 3-Nitro-4-(4-fluorobenzyloxy)acetophenone; 4'-Fluorobenzyloxy-3'-nitroacetophenone; 1-(4-((4-Fluorobenzyl)oxy)-3-nitrophenyl)ethan-1-one; Acetophenone, 4-(4-fluorobenzyloxy)-3-nitro-
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Fluorobenzyloxy)-3-Nitroacetophenone is manufactured under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.