Description

2-Bromo-1-Chloro-3-Methoxybenzene is a versatile halogenated anisole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce both bromine and chlorine substituents in a single, controlled step, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the methoxy and halogen groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex molecular architectures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and process chemistry optimization in R&D laboratories.

Basic Information

Product Name	2-Bromo-1-Chloro-3-Methoxybenzene
CAS No.	174913-08-7
Molecular Formula	C7H6BrClO
Molecular Weight	221.48 g/mol
Synonyms	1-Bromo-2-Chloro-3-Methoxybenzene; 2-Chloro-6-Bromoanisole; 3-Methoxy-2-Chlorobromobenzene; 2-Bromo-1-Chloro-3-Methoxybenzene; 2-Chloro-6-methoxybromobenzene; 2-Chloro-6-bromoanisole; 2-Bromo-6-chloroanisole; 1-Chloro-2-bromo-3-methoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Chloro-3-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.