Description

Ethanone, 2,2,2-Trifluoro-1-(2-Thiazolyl)- (9Ci) is a specialized fluorinated thiazole derivative, serving as a high-value synthetic intermediate in advanced chemical manufacturing. Its core value lies in the unique trifluoroacetyl group attached to the thiazole heterocycle, enabling precise molecular modifications for performance-driven applications. This compound is essential for R&D and production teams in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the thiazole moiety for biological activity.
• Material Science Research: Serves as a precursor for advanced organic electronic materials and liquid crystals due to its fluorinated aromatic structure.
• Chemical Biology & Proteomics: Employed as a reactive handle or labeling agent in the study of protein interactions and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical producers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(2-Thiazolyl)- (9Ci)
CAS No.	174824-75-0
Molecular Formula	C5H2F3NOS
Molecular Weight	181.14 g/mol
Synonyms	2,2,2-Trifluoro-1-(1,3-thiazol-2-yl)ethanone; 2,2,2-Trifluoro-1-(2-thiazolyl)ethanone; 2-(Trifluoroacetyl)thiazole; 1-(1,3-Thiazol-2-yl)-2,2,2-trifluoroethanone; 2-Thiazolyl trifluoromethyl ketone; Trifluoroacetylthiazole; TFAT
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(2-Thiazolyl)- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, verified by advanced analytical techniques including HPLC, GC, and NMR. We adhere to cGMP principles where applicable to meet the stringent requirements of our global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.