Description

Chloro{[(1S,2S)-(+)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(Mesitylene)Ruthenium(II), Min. 90% RuCl[(S,S)-TsDPEN](mesitylene) is a high-purity, chiral ruthenium complex widely recognized as a premier asymmetric hydrogenation catalyst. This compound is valued for its exceptional enantioselectivity and catalytic efficiency in the synthesis of optically active intermediates. It is a critical reagent for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to establish or scale up stereoselective synthetic routes.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key for manufacturing active pharmaceutical ingredients (APIs) requiring high enantiomeric purity, such as β-amino alcohols and chiral amines.
• Fine Chemical Production: Enables the synthesis of specialty chemicals, flavors, and fragrances with precise stereochemistry.
• Methodology Development: An essential tool in academic and industrial research laboratories for developing new catalytic asymmetric transformations.
• Process Chemistry Optimization: Used to improve the yield, selectivity, and sustainability of existing chemical manufacturing processes.

Basic Information

Product Name	Chloro{[(1S,2S)-(+)-2-Amino-1,2-Diphenylethyl](4-Toluenesulfonyl)Amido}(Mesitylene)Ruthenium(II), Min. 90% RuCl[(S,S)-TsDPEN](mesitylene)
CAS No.	174813-81-1
Molecular Formula	C30H33ClN2O2RuS
Molecular Weight	610.18 g/mol
Synonyms	RuCl[(S,S)-TsDPEN](p-cymene); (S,S)-RuCl(TsDPEN)(p-cymene); (S,S)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Ruthenium (II) Chloride Complex; (1S,2S)-N-(4-Methylbenzenesulfonyl)-1,2-diphenylethane-1,2-diamine Chloro(mesitylene)ruthenium(II); Noyori-Ikariya Catalyst; Asymmetric Transfer Hydrogenation Catalyst; Ruthenium TsDPEN Catalyst; Ru-TsDPEN-p-cymene Complex
EINECS	Contact for details

Quality Control

Our RuCl[(S,S)-TsDPEN](mesitylene) is manufactured under controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the stringent requirements of process chemistry and API synthesis. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will compromise its catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	Min. 90%
Chiral Purity (HPLC)	Min. 99% ee
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.