Description

2-Propenoic Acid, 3-(2-Chloro-4-fluorophenyl)-, (2E)- is a high-purity, advanced pharmaceutical intermediate characterized by its specific (E)-alkene configuration. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, where precise stereochemistry and functional group integrity are paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research and development.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized organic molecules used in electronic displays.
• Polymer Modification Agent: Employed to introduce specific functional groups into polymer chains to alter material properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and other advanced organic transformations in laboratory and pilot-scale settings.
• Chemical Research Standard: Acts as a reference standard or analytical reagent in quality control and method development.

Basic Information

Item	Detail
Product Name	2-Propenoic Acid, 3-(2-Chloro-4-fluorophenyl)-, (2E)-
CAS No.	174603-37-3
Molecular Formula	C9H6ClFO2
Molecular Weight	200.59 g/mol
Synonyms	(E)-3-(2-Chloro-4-fluorophenyl)acrylic acid; trans-3-(2-Chloro-4-fluorophenyl)-2-propenoic acid; 2-Chloro-4-fluorocinnamic acid; (E)-2-Chloro-4-fluorocinnamic acid; (2E)-3-(2-Chloro-4-fluorophenyl)prop-2-enoic acid; 3-(2-Chloro-4-fluorophenyl)acrylic acid (E-isomer); 174603-37-3
EINECS	Contact for details

Quality Control

Our 2-Propenoic Acid, 3-(2-Chloro-4-fluorophenyl)-, (2E)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Isomeric Purity (E-isomer)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.