Description

Cyclopropanecarboxylic Acid, 2,2-Dimethyl-3-Nitro-, Ethyl Ester (9Ci) is a specialized nitrocyclopropane derivative, a high-value intermediate prized for its unique sterically hindered and functionalized cyclopropane ring system. This compound matters for its role in advanced synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring constrained three-dimensional pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclopropane moiety can impart specific biological activity and metabolic stability.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial research for cyclopropanation reactions, [3+2] cycloadditions, and the study of strained ring chemistry.
• Ligand and Catalyst Development: Utilized as a scaffold for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2,2-Dimethyl-3-Nitro-, Ethyl Ester (9Ci)
CAS No.	174574-81-3
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	Ethyl 2,2-Dimethyl-3-nitrocyclopropanecarboxylate; 2,2-Dimethyl-3-nitrocyclopropanecarboxylic Acid Ethyl Ester; 3-Nitro-2,2-dimethylcyclopropanecarboxylic Acid Ethyl Ester; Nitrocyclopropane Carboxylate Ester; 9CI Labeled Compound; (2,2-Dimethyl-3-nitrocyclopropyl)formic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2,2-Dimethyl-3-Nitro-, Ethyl Ester (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.