Description

Cyclopropanecarboxylic Acid, 2-(1-Methylethyl)-3-Nitro-, Ethyl Ester (9Ci) is a specialized nitrocyclopropane derivative, a high-value chemical intermediate prized for its unique sterically hindered and electron-deficient cyclopropane ring system. This compound is critical for enabling advanced synthetic transformations in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the cyclopropane pharmacophore into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the cyclopropane moiety can enhance biological activity and environmental stability.
• Fine Chemical Synthesis: Acts as a versatile precursor for creating other functionalized cyclopropane derivatives used in material science and specialty chemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis, including cyclopropanation reactions and nitro group manipulations.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(1-Methylethyl)-3-Nitro-, Ethyl Ester (9Ci)
CAS No.	174574-80-2
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	Ethyl 2-Isopropyl-3-nitrocyclopropanecarboxylate; 2-Isopropyl-3-nitrocyclopropanecarboxylic Acid Ethyl Ester; 3-Nitro-2-(propan-2-yl)cyclopropane-1-carboxylic acid ethyl ester; Nitrocyclopropane ester intermediate; 2-(1-Methylethyl)-3-nitrocyclopropanecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 2-(1-Methylethyl)-3-Nitro-, Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.