Description

Ethyl 3-Azabicyclo[3.1.0]Hexane-6-Carboxylate is a high-value, synthetically versatile bicyclic organic compound featuring a fused cyclopropane-pyrrolidine (3-azabicyclo[3.1.0]hexane) scaffold. This structure makes it a critical pharmaceutical intermediate and key building block for medicinal chemistry research, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D and process chemistry teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, antiviral agents, and other therapeutic areas.
• Medicinal Chemistry Building Block: Used to introduce the constrained 3-azabicyclo[3.1.0]hexane moiety, which can improve potency, selectivity, and metabolic stability of lead compounds.
• Agrochemical Research: Serves as an intermediate in the development of new pesticides and herbicides with novel modes of action.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	Ethyl 3-Azabicyclo[3.1.0]Hexane-6-Carboxylate
CAS No.	174456-77-0
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Ethyl 3-azabicyclo[3.1.0]hexane-6-carboxylate; 6-(Ethoxycarbonyl)-3-azabicyclo[3.1.0]hexane; Ethyl 6-azabicyclo[3.1.0]hexane-3-carboxylate (registry number specific); 3-Azabicyclo[3.1.0]hexane-6-carboxylic acid ethyl ester; Bicyclic proline derivative; 3-Aza-6-carbethoxybicyclo[3.1.0]hexane; Fused cyclopropane-pyrrolidine ester.
EINECS	Contact for details

Quality Control

Our Ethyl 3-Azabicyclo[3.1.0]Hexane-6-Carboxylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.