Description

Methanesulfonamide, 1,1,1-Trifluoro-n-Nitro-, Ion(1-) (9Ci) is a specialized fluorinated sulfonamide anion, a high-value intermediate in advanced organic synthesis. This compound matters for its unique trifluoromethyl and nitro-substituted sulfonamide structure, which is critical for modulating the physicochemical properties of target molecules, particularly in pharmaceutical development. It is primarily needed by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for functionalized ionic liquids or specialty polymers with tailored electronic or surface properties.
• Fluorination Chemistry: Acts as a source of a stabilized anionic moiety in nucleophilic substitution reactions to introduce complex sulfonamide functionalities.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	Methanesulfonamide, 1,1,1-Trifluoro-n-Nitro-, Ion(1-) (9Ci)
CAS No.	174191-41-4
Molecular Formula	C₂H₂F₃N₂O₄S⁻
Molecular Weight	190.11 g/mol
Synonyms	1,1,1-Trifluoro-N-nitro-methanesulfonamide anion; Trifluoromethanesulfonamide, N-nitro-, ion(1-); N-Nitro-1,1,1-trifluoromethanesulfonamide anion; 1,1,1-Trifluoro-N-nitro-methanesulfonamide (anion); (1,1,1-Trifluoro-N-nitro-methanesulfonamido)ate; 9CI Index Name; 174191-41-4 (CAS)
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, 1,1,1-Trifluoro-n-Nitro-, Ion(1-) (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity advanced intermediates under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.