Description

Fmoc-P(Nh-Boc)-L-Phe-Oh is a protected amino acid derivative widely used in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled introduction of specific amino acid residues, enabling the production of complex peptides and peptidomimetics. It is a critical building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Key intermediate in the solid-phase synthesis of therapeutic peptides and proteins.
• Building block for the research and development of novel peptidomimetics and drug candidates.
• Used in the preparation of custom peptides for biochemical and pharmacological studies.
• Essential reagent in combinatorial chemistry libraries for drug discovery.
• Intermediate in the synthesis of peptide-based diagnostic reagents and biomarkers.
• Starting material for advanced conjugate vaccines and targeted delivery systems.

Basic Information

Product Name	Fmoc-P(Nh-Boc)-L-Phe-Oh
CAS No.	174132-31-1
Molecular Formula	C30H32N2O6
Molecular Weight	516.59 g/mol
Synonyms	Fmoc-Phe(P(NHBoc))-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(1,1-dimethylethoxy)carbonyl]-L-phenylalaninamide; Fmoc-L-Phe(P(NH-Boc))-OH; Fmoc-Phe(P(NH-Boc))-OH; Nα-Fmoc-Nβ-Boc-L-2,3-diaminopropionic acid (Phe derivative); Boc-NH-P(NH-Fmoc)-Phe-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((((tert-butoxycarbonyl)amino)(phenyl)methyl)amino)propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-P(Nh-Boc)-L-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.