Description

4,4,5,5-Tetramethyl-2-(1-Phenylethyl)-1,3,2-Dioxaborolane is a valuable organoboron reagent, specifically a pinacol boronic ester, widely used in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, a critical step in constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing biaryl and heterobiaryl motifs prevalent in active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl-alkyl linkages.
• Material Science & OLED Research: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional organic electronic compounds.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or creating molecular probes for diagnostic applications.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(1-Phenylethyl)-1,3,2-Dioxaborolane
CAS No.	174090-36-9
Molecular Formula	C14H21BO2
Molecular Weight	232.13 g/mol
Synonyms	(1-Phenylethyl)boronic acid pinacol ester; 1-Phenylethylboronic acid pinacol ester; α-Methylbenzylboronic acid pinacol ester; (1-Phenylethyl)pinacolborane; (α-Methylbenzyl)boronic acid pinacol ester; 2-(1-Phenylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (R/S)-1-Phenylethylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(1-Phenylethyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.