Description

1-Pyrrolidinecarboxylic Acid, 3,3-Difluoro-4-(Hydroxymethyl)-, Phenylmethyl Ester is a high-purity, fluorinated pyrrolidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates both fluorine atoms and a protected hydroxymethyl group, enabling precise modifications in target molecules. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the fluorinated pyrrolidine structure can enhance stability and bioactivity.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for exploring new chemical entities and reaction pathways.
• Peptidomimetics Development: Employed in the design and synthesis of peptidomimetic compounds, which mimic peptides but with improved metabolic stability.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands for catalytic systems.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 3,3-Difluoro-4-(Hydroxymethyl)-, Phenylmethyl Ester
CAS No.	174073-95-1
Molecular Formula	C13H15F2NO3
Molecular Weight	271.26 g/mol
Synonyms	Benzyl 3,3-difluoro-4-(hydroxymethyl)pyrrolidine-1-carboxylate; 3,3-Difluoro-4-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid Phenylmethyl Ester; 1-(Benzyloxycarbonyl)-3,3-difluoro-4-(hydroxymethyl)pyrrolidine; 1-Cbz-3,3-difluoro-4-(hydroxymethyl)pyrrolidine; 1-N-Cbz-3,3-difluoro-4-hydroxymethylpyrrolidine; (3,3-Difluoro-4-hydroxymethyl-pyrrolidin-1-yl)-carboxylic acid benzyl ester; N-Cbz-3,3-difluoro-4-(hydroxymethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylic Acid, 3,3-Difluoro-4-(Hydroxymethyl)-, Phenylmethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.