Description

5-Methylpyridine-3-Boronic Acid is a high-purity boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyridine and bipyridine scaffolds.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as those for OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biological target identification.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	5-Methylpyridine-3-Boronic Acid
CAS No.	173999-18-3
Molecular Formula	C6H8BNO2
Molecular Weight	136.95 g/mol
Synonyms	(5-Methyl-3-pyridinyl)boronic Acid; 3-Borono-5-methylpyridine; 5-Methyl-3-pyridineboronic Acid; 5-Methylpyridin-3-ylboronic Acid; 3-Pyridineboronic Acid, 5-methyl-; 5-Methyl-3-pyridylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 5-Methylpyridine-3-Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay (HPLC), identity (NMR/IR), and impurity profiles. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.