Description

4-(2,4-Difluorophenoxy)-3-Nitrobenzenecarbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic aldehyde and nitro-substituted difluorophenoxy structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated molecules for enhanced bioavailability and metabolic stability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated drug candidates, particularly for oncology and central nervous system (CNS) therapies.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the difluorophenoxy moiety contributes to biological activity.
• Organic Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and fine chemicals in laboratory and pilot-scale operations.
• Material Science: Investigated for the preparation of specialized polymers and liquid crystals that incorporate fluorinated aromatic units.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client-specific molecules.

Basic Information

Product Name	4-(2,4-Difluorophenoxy)-3-Nitrobenzenecarbaldehyde
CAS No.	173282-22-9
Molecular Formula	C13H7F2NO4
Molecular Weight	279.20 g/mol
Synonyms	3-Nitro-4-(2,4-difluorophenoxy)benzaldehyde; 4-(2,4-Difluorophenoxy)-3-nitrobenzaldehyde; Benzaldehyde, 4-(2,4-difluorophenoxy)-3-nitro-; 173282-22-9; 4-(2,4-Difluorophenoxy)-3-nitro-benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-(2,4-Difluorophenoxy)-3-Nitrobenzenecarbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.