Description

Cyclohexanone, 2,3-Difluoro-3-Methyl-, cis- (9Ci) CAS NO 172969-00-5 is a specialized fluorinated cyclohexanone derivative, a high-value building block in advanced organic synthesis. Its unique cis-configuration and fluorine substitution pattern make it a critical intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated motifs that can enhance metabolic stability, bioavailability, and binding affinity in active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated, stereochemically defined cyclohexyl rings.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms can improve lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor in the synthesis of fluorinated organic compounds for electronic applications, contributing to the dielectric anisotropy and thermal stability of display materials.
• Advanced Polymer Chemistry: Employed in the creation of specialty monomers for high-performance polymers with specific chemical resistance and low surface energy properties.
• Asymmetric Catalysis & Chiral Pool: Utilized as a chiral starting material or ligand precursor in stereoselective synthesis due to its defined cis-stereochemistry.
• Fluorine Chemistry Research: A valuable compound for academic and industrial R&D focused on exploring new reactions and properties of aliphatic fluorinated systems.

Basic Information

Product Name	Cyclohexanone, 2,3-Difluoro-3-Methyl-, cis- (9Ci)
CAS No.	172969-00-5
Molecular Formula	C7H10F2O
Molecular Weight	148.15 g/mol
Synonyms	cis-2,3-Difluoro-3-methylcyclohexanone; (1R,2S,3S)-2,3-Difluoro-3-methylcyclohexanone; 2,3-Difluoro-3-methylcyclohexanone (cis-); 3-Methyl-2,3-difluorocyclohexanone; Fluorinated Cyclohexanone Derivative; 172969-00-5; cis-3-Methyl-2,3-difluorocyclohexanone
EINECS	Contact for details

Quality Control

Our Cyclohexanone, 2,3-Difluoro-3-Methyl-, cis- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (typically by GC/HPLC), enantiomeric excess, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC / HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.