Description

Cyclohexanone, 2,3-Difluoro-2-Methyl-, cis- (9Ci) is a specialized fluorinated cyclohexanone derivative, a high-value building block prized for its unique stereochemistry and fluorine substitution pattern. This compound is critical for introducing structural complexity and modifying physicochemical properties in advanced synthetic pathways. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides where fluorine atoms enhance bioavailability and environmental stability.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the production of specialty polymers, liquid crystals, and fluorinated coatings.
• Organic Synthesis Building Block: Employed in asymmetric synthesis, catalysis research, and the construction of complex natural product analogs.
• Fluorine Chemistry Studies: A valuable reference compound for investigating the stereoelectronic effects of gem-difluoro and adjacent fluorine substituents on cyclohexanone reactivity.

Basic Information

Item	Detail
Product Name	Cyclohexanone, 2,3-Difluoro-2-Methyl-, cis- (9Ci)
CAS No.	172968-86-4
Molecular Formula	C7H10F2O
Molecular Weight	148.15 g/mol
Synonyms	cis-2,3-Difluoro-2-methylcyclohexanone; 2-Methyl-2,3-difluorocyclohexanone, cis-; (1R,2S)-2,3-Difluoro-2-methylcyclohexanone (and other stereoisomers); 2,3-Difluoro-2-methylcyclohexanone; 172968-86-4; Fluorinated cyclohexanone derivative
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and isomeric composition. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. Our commitment to quality supports compliance with ISO 9001 standards and the stringent requirements of global R&D supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the potential sensitivity of fluorinated ketones, prolonged exposure to air and moisture should be minimized.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Isomeric Purity (cis-)	≥ 90.0% (by GC or NMR)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.