Description

2-[Hydroxy(Phenyl)Phosphoryl]-1-Methyl-1H-Benzimidazole is a specialized organophosphorus compound featuring a benzimidazole core, which is of significant interest in advanced chemical synthesis and materials science. This molecule serves as a key intermediate or ligand in the development of pharmaceuticals, agrochemicals, and functional materials due to its unique electronic and coordination properties. It is primarily sought by research institutions and industrial manufacturers in the fine chemical, pharmaceutical, and catalyst development sectors for creating novel compounds with enhanced biological or catalytic activity.

Application

• As a key synthetic intermediate in the research and development of novel pharmaceutical active ingredients, particularly kinase inhibitors and antiviral agents.
• Utilized as a chelating ligand or catalyst precursor in transition metal catalysis for organic transformations, including cross-coupling and phosphorylation reactions.
• Potential application in the synthesis of advanced agrochemicals, such as herbicides or plant growth regulators, leveraging its bioactive scaffold.
• Used in material science research for the development of metal-organic frameworks (MOFs) or functional polymers with specific optical or electronic properties.
• Acts as a building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Serves as a reference standard or analytical reagent in quality control laboratories for method development and validation.

Basic Information

Product Name	2-[Hydroxy(Phenyl)Phosphoryl]-1-Methyl-1H-Benzimidazole
CAS No.	172753-91-2
Molecular Formula	C14H13N2O2P
Molecular Weight	272.24 g/mol
Synonyms	1-Methyl-2-(hydroxy(phenyl)phosphoryl)-1H-benzimidazole; 2-(Hydroxy(phenyl)phosphoryl)-1-methylbenzimidazole; 1-Methyl-2-(phenylphosphono)-1H-benzimidazole; Phenyl(1-methyl-1H-benzimidazol-2-yl)phosphinic acid; 1-Methyl-2-(phenylphosphinyl)-1H-benzimidazole; 2-(Hydroxyphenylphosphoryl)-1-methylbenzimidazole; (1-Methyl-1H-benzimidazol-2-yl)(phenyl)phosphinic acid
EINECS	Contact for details

Quality Control

Our production of 2-[Hydroxy(Phenyl)Phosphoryl]-1-Methyl-1H-Benzimidazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.