Description

2-Chlorophenylboronic Acid-1,3-Propanediol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the parent boronic acid, making it ideal for handling, storage, and controlled reactivity in sensitive processes. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for Suzuki-Miyaura cross-coupling reactions to construct complex biaryl scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated biaryl structures.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and sensors.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Scale-up: Supports contract research organizations (CROs) and fine chemical manufacturers in developing custom synthetic routes from lab to pilot scale.

Basic Information

Product Name	2-Chlorophenylboronic Acid-1,3-Propanediol Ester
CAS No.	172732-59-1
Molecular Formula	C9H10BClO3
Molecular Weight	212.44 g/mol
Synonyms	2-Chlorophenylboronic Acid Propylene Glycol Ester; 1,3-Propanediol, 2-(2-chlorophenyl)-1,3,2-dioxaborolane; 2-(2-Chlorophenyl)-1,3,2-dioxaborolane; 2-Chlorobenzeneboronic Acid 1,3-Propanediol Cyclic Ester; (2-Chlorophenyl)boronic Acid 1,3-Propanediol Ester; 2-Chlorophenyl-1,3,2-dioxaborolane; Boronic acid, B-(2-chlorophenyl)-, 1,3-propanediyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-Chlorophenylboronic Acid-1,3-Propanediol Ester is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.