Description

1,3,2-Dioxaborolane, 2-[(1E)-2-Cyclohexylethenyl]-4,4,5,5-Tetramethyl- is a high-purity, organoboron reagent featuring a vinylboronate ester group, a key intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery, catalyst development, and polymer synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional polymers with tailored electronic properties.
• Ligand & Catalyst Preparation: Employed in the development of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Probe Synthesis: Utilized for labeling biomolecules or creating molecular probes for diagnostic and research applications.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[(1E)-2-Cyclohexylethenyl]-4,4,5,5-Tetramethyl-
CAS No.	172512-85-5
Molecular Formula	C₁₄H₂₅BO₂
Molecular Weight	236.16 g/mol
Synonyms	2-[(1E)-2-Cyclohexylethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(2-Cyclohexylvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; trans-2-(2-Cyclohexylvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclohexylvinylboronic Acid Pinacol Ester; (E)-Cyclohexylvinylboronic Acid Pinacol Ester; (E)-2-Cyclohexylvinylboronic Acid Pinacol Ester; CyclohexylvinylBPin
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxaborolane, 2-[(1E)-2-Cyclohexylethenyl]-4,4,5,5-Tetramethyl- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Isomeric Purity (E/Z)	≥95% (E-isomer)
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.