Description

Cek11/Fc Chimera CAS NO 172306-57-9 is a specialized engineered protein construct, typically a fusion of a targeting domain (like an antibody fragment) with an effector domain (such as an Fc region). This molecular design is critical for creating targeted therapeutic agents with enhanced stability and pharmacokinetic properties. It is primarily required by biopharmaceutical R&D teams and manufacturers developing next-generation biologics, including bispecific antibodies, antibody-drug conjugates (ADCs), and targeted immunotherapies.

Application

• Bispecific Antibody Development: Serves as a key intermediate or reference standard for constructing bispecific antibodies that engage two different antigens.
• Antibody-Drug Conjugate (ADC) Platforms: Used in the research and production of ADCs, where the chimera provides targeted delivery of cytotoxic payloads.
• Targeted Cancer Immunotherapy: Acts as a core component in the development of novel immunotherapies designed to redirect immune cells to tumor sites.
• Protein Engineering & Validation: Employed as a critical reagent for validating protein expression systems, purification protocols, and functional assays.
• Diagnostic Reagent Production: Utilized in the manufacture of high-sensitivity diagnostic kits and imaging probes requiring specific targeting.
• Stability & PK/PD Studies: Functions as a model compound to study the impact of Fc fusion on serum half-life, stability, and pharmacodynamics.

Basic Information

Product Name	Cek11/Fc Chimera
CAS No.	172306-57-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CEK11-Fc Fusion Protein; Fc-CEK11 Chimera; Anti-CEK11 Fc Fusion Protein; Recombinant CEK11/Fc; Immunoglobulin Fc Region Fusion with CEK11; CEK11 Immunoadhesin; Fc Tagged CEK11 Protein; 172306-57-9
EINECS	Contact for details

Quality Control

Every batch of Cek11/Fc Chimera is produced and tested under stringent quality management systems. Our products undergo rigorous analytical testing, including SDS-PAGE, SEC-HPLC, and endotoxin assays, to ensure identity, purity, potency, and safety for research use. Certificates of Analysis (COA) detailing lot-specific results are available upon request, supporting compliance with critical R&D and pre-clinical development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product should be handled under aseptic conditions to prevent microbial contamination. The lyophilized powder is hygroscopic and should be kept in a dry environment.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to reference standard
Purity (SEC-HPLC)	≥ 95%
Protein Content (UV Absorption)	≥ 90% of label claim
Endotoxin (LAL Test)	< 1.0 EU/µg
Biological Activity (Binding Assay)	Contact for details
Solubility	Soluble in sterile PBS or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.