Description

1,4-Dioxa-8-Aza-Spiro[4.6]Undecan-9-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex spirocyclic and heterocyclic drug candidates, particularly for central nervous system (CNS) and antiviral applications.
• Organic Synthesis Reagent: Used in advanced organic chemistry for constructing complex molecular architectures, leveraging its reactive ketone and protected amine functionalities.
• Research & Development (R&D): Essential for medicinal chemistry programs in academic, biotech, and pharmaceutical R&D labs for exploring new chemical entities.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Potential intermediate in the development of novel agrochemicals with specific biological activity.

Basic Information

Product Name	1,4-Dioxa-8-Aza-Spiro[4.6]Undecan-9-One
CAS No.	172090-55-0
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	8-Aza-1,4-dioxaspiro[4.6]undecan-9-one; 1,4-Dioxa-8-azaspiro[4.6]undecan-9-one; 9-Oxo-1,4-dioxa-8-azaspiro[4.6]undecane; 2-Oxospiro[1,3-dioxolane-2,4'-piperidine]; 1,4-Dioxa-8-azaspiro[4.6]undecan-9-one; Spirocyclic ketone intermediate
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-8-Aza-Spiro[4.6]Undecan-9-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production can be aligned with GMP guidelines for pharmaceutical applications. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.