Description

Carbamic Acid, (3-Formylcyclobutyl)-, 1,1-Dimethylethyl Ester, cis- (9Ci) is a specialized, high-purity chemical intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique cis-cyclobutyl scaffold bearing both formyl and protected carbamate functionalities, making it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for process chemistry applications.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring constrained, three-dimensional structures.
• Agrochemical Synthesis: Used in the development of new generation herbicides, fungicides, or insecticides where the cyclobutane ring can impart favorable biological activity and metabolic stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probe Development: Utilized in medicinal chemistry for creating molecular probes to study enzyme function or protein-ligand interactions due to its reactive aldehyde and protected amine groups.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex target molecules.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	Carbamic Acid, (3-Formylcyclobutyl)-, 1,1-Dimethylethyl Ester, cis- (9Ci)
CAS No.	171549-91-0
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	cis-tert-Butyl (3-formylcyclobutyl)carbamate; (cis)-N-Boc-3-formylcyclobutanamine; cis-3-[(tert-Butoxycarbonyl)amino]cyclobutanecarboxaldehyde; 1,1-Dimethylethyl cis-(3-formylcyclobutyl)carbamate; cis-N-Boc-3-Aminocyclobutanecarboxaldehyde; Boc-ACCA-aldehyde (cis); (cis)-3-((tert-Butoxycarbonyl)amino)cyclobutanecarbaldehyde
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (3-Formylcyclobutyl)-, 1,1-Dimethylethyl Ester, cis- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.