Description

4,4,5,5-Tetramethyl-2-(2,4,6-Trimethylphenyl)-1,3,2-Dioxaborolane is a high-purity, sterically hindered boronic ester derivative, serving as a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it an indispensable reagent for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for carbon-carbon bond formation. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for complex, multi-substituted aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer & Material Science: Employed in the creation of specialty polymers, liquid crystals, and organic semiconductors with tailored electronic properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Ligand & Catalyst Preparation: Used in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2,4,6-Trimethylphenyl)-1,3,2-Dioxaborolane
CAS No.	171364-84-4
Molecular Formula	C15H23BO2
Molecular Weight	246.15 g/mol
Synonyms	2-(2,4,6-Trimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Mesitylboronic Acid Pinacol Ester; 2-Mesityl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,4,6-Trimethylphenylboronic Acid Pinacol Ester; MesitylBPin; (2,4,6-Trimethylphenyl)boronic Acid Pinacol Ester; 171364-84-4; Pinacol Mesitylboronate
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2,4,6-Trimethylphenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for sensitive applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.