Description

Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and conductive polymers.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming reactions and creating compound libraries.
• Liquid Crystal and Polymer Chemistry: Intermediate in the production of monomers and polymers with specific aromatic architectures for advanced material properties.

Basic Information

Product Name	Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	171364-80-0
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 4-(pinacolboryl)benzoate; Methyl p-(pinacolboryl)benzoate; 4-(Methoxycarbonyl)phenylboronic acid pinacol ester; 4-Carbomethoxyphenylboronic acid pinacol ester; Pinacol 4-(methoxycarbonyl)phenylboronate; Benzoic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.