Description

4-Methoxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical, air-stable building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing biaryl motifs, particularly for drug discovery and development programs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Advanced Material Research: Employed in the construction of organic electronic materials, such as those used in OLEDs and semiconductors, where precise molecular architecture is required.
• Chemical Biology Probes: Utilized in the preparation of boronic acid-based probes and sensors for detecting biological analytes.
• Scale-up Process Chemistry: Its pinacol ester form offers improved stability and handling properties, making it suitable for pilot plant and manufacturing-scale coupling reactions.

Basic Information

Product Name	4-Methoxyphenylboronic Acid, Pinacol Ester
CAS No.	171364-79-7
Molecular Formula	C13H19BO3
Molecular Weight	234.10 g/mol
Synonyms	4-Methoxyphenylboronic Acid Pinacol Ester; (4-Methoxyphenyl)boronic Acid Pinacol Ester; 2-(4-Methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Methoxybenzeneboronic Acid Pinacol Ester; 4-Anisylboronic Acid Pinacol Ester; Pinacol (4-Methoxyphenyl)boronate; 4-Methoxy Phenyl B Pinacol Ester
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure consistency and high purity. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles as determined by NMR, HPLC, and GC analysis. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.