Description

Hydroxyethyl β-Cyclodextrin is a chemically modified derivative of β-cyclodextrin, engineered to enhance solubility and stability for complexation. This high-purity excipient is critical for improving the bioavailability and delivery of poorly soluble active pharmaceutical ingredients. It serves as an essential solubilizing and stabilizing agent for pharmaceutical, nutraceutical, and advanced material research and development.

Application

• Pharmaceutical Formulations: As a solubility enhancer and stabilizer for injectable, oral, and topical drug products.
• Drug Delivery Systems: For the preparation of inclusion complexes to mask taste, odor, or control release rates.
• Biotechnology & Research: Used in cell culture media and as a stabilizing agent for proteins, enzymes, and other biomolecules.
• Cosmetics & Personal Care: Acts as a carrier for fragrances, vitamins, and active ingredients in creams and serums.
• Food & Flavor Industry: For the encapsulation and protection of sensitive flavors, colors, and nutrients.
• Analytical Chemistry: Employed as a chiral selector in capillary electrophoresis and chromatographic separations.
• Chemical Synthesis: As a green chemistry catalyst or reaction mediator in organic synthesis.

Basic Information

Product Name	Hydroxyethyl β-Cyclodextrin
CAS No.	170744-18-0
Molecular Formula	(C6H10O5)7·(C2H4O)n
Molecular Weight	~1135 g/mol (base) + substitution-dependent
Synonyms	2-Hydroxyethyl-β-cyclodextrin; HE-β-CD; Hydroxyethyl-β-cyclodextrin; HEBCD; β-Cyclodextrin, 2-hydroxyethyl ether; (2-Hydroxyethyl)-β-cyclodextrin; Hydroxyethylated β-Cyclodextrin; HEB
EINECS	Contact for details

Quality Control

Our Hydroxyethyl β-Cyclodextrin is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets stringent specifications for pharmaceutical and research applications. We can supply grades compliant with in-house pharmacopeial standards (e.g., USP/NF, EP monographs for related cyclodextrins). A comprehensive Certificate of Analysis (COA) detailing identity, purity, substitution degree, and critical impurities is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed to prevent absorption of moisture from the air, which can affect product performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Degree of Substitution (DS)	Specified range (e.g., 0.6 - 0.9)
Water Content (KF)	≤ 10.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	< 0.5 EU/mg (for injectable grade)
Microbial Enumeration	Meets specified limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.