Description

5-(4-Fluorophenyl) Isothiazole is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is particularly significant for its role in the development of novel pharmaceuticals and agrochemicals, where the isothiazole core and fluorine substituent impart unique biological activity and metabolic stability. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and insecticides, leveraging the bioactivity of the isothiazole ring.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	5-(4-Fluorophenyl) Isothiazole
CAS No.	170696-25-0
Molecular Formula	C9H6FNS
Molecular Weight	179.21 g/mol
Synonyms	5-(4-Fluorophenyl)-1,2-thiazole; 4-Fluorophenylisothiazole; 5-(p-Fluorophenyl)isothiazole; Isothiazole, 5-(4-fluorophenyl)-; 1,2-Thiazole, 5-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl) Isothiazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.