Description

4,4-Difluoro-1-(3-Fluoro-4-Methoxyphenyl)Butane-1,3-Dione is a high-purity fluorinated diketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring multiple fluorine atoms and a methoxyphenyl group, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing fluorinated heterocycles and complex scaffolds.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for novel fluorinated polymers, ligands for catalysis, and organic electronic materials.
• Chemical Research & Development: Employed in method development and as a standard in analytical laboratories for studying fluorination reactions and diketone chemistry.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized chelating agents and catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	4,4-Difluoro-1-(3-Fluoro-4-Methoxyphenyl)Butane-1,3-Dione
CAS No.	170570-77-1
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	1,3-Butanedione, 4,4-difluoro-1-(3-fluoro-4-methoxyphenyl)-; 4,4-Difluoro-1-(3-fluoro-4-methoxyphenyl)-1,3-butanedione; 3-Fluoro-4-methoxyphenyl 4,4-difluorodiketone; 4,4,3'-Trifluoro-4'-methoxydibenzoylmethane (partial structural analog); DFMPBD (abbreviation); (3-Fluoro-4-methoxyphenyl)(4,4-difluoro-3-oxobutyl) ketone
EINECS	Contact for details

Quality Control

Our production of 4,4-Difluoro-1-(3-Fluoro-4-Methoxyphenyl)Butane-1,3-Dione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality systems are designed to meet the exacting standards required for research and cGMP-grade pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.