Description

3'-(Trifluoromethoxy)Acetophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role in introducing the unique physicochemical properties of the trifluoromethoxy group into target molecules, enhancing metabolic stability and lipophilicity. Pharmaceutical, agrochemical, and material science researchers need it for the development of novel active ingredients and functional materials. Its precise structure makes it a critical intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in CNS and metabolic disease research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethoxy group improves bioactivity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies, influencing dielectric anisotropy and emission properties.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and optical characteristics.
• Organic Synthesis & Catalysis Research: A versatile substrate for cross-coupling reactions, carbonyl chemistry, and methodological studies in fluoroorganic chemistry.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and tags for imaging and diagnostic applications due to its fluorine signature.

Basic Information

Product Name	3'-(Trifluoromethoxy)Acetophenone
CAS No.	170141-63-6
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	1-[3-(Trifluoromethoxy)phenyl]ethanone; 3-Acetylphenyl trifluoromethyl ether; m-(Trifluoromethoxy)acetophenone; 3-Trifluoromethoxyacetophenone; 3'-Trifluoromethoxyacetophenone; 1-(3-Trifluoromethoxyphenyl)ethan-1-one; Ethanone, 1-[3-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 3'-(Trifluoromethoxy)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.